Affordable Access

Publisher Website

Glycoprotein 60 diversity inC. hominisandC. parvumcausing human cryptosporidiosis in NSW, Australia

Authors
Journal
Experimental Parasitology
0014-4894
Publisher
Elsevier
Publication Date
Volume
122
Issue
2
Identifiers
DOI: 10.1016/j.exppara.2009.02.006
Keywords
  • Cryptosporidium
  • Cryptosporidiosis
  • Diarrhoea
  • Human Disease
  • Gp60
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Management and control of cryptosporidiosis in human requires knowledge of Cryptosporidium species contributing to human disease. Markers that are able to provide information below the species level have become important tools for source tracking. Using the hypervariable surface antigen, glycoprotein 60 (GP60), C. hominis ( n = 37) and C. parvum ( n = 32) isolates from cryptosporidiosis cases in New South Wales, Australia, were characterised. Extensive variation was observed within this locus and the isolates could be divided into 8 families and 24 different subtypes. The subtypes identified have global distributions and indicate that anthroponotic and zoonotic transmission routes contribute to sporadic human cryptosporidiosis in NSW.

There are no comments yet on this publication. Be the first to share your thoughts.