Affordable Access

Near Infra-Red Reflectance Spectroscopic Determination of Metformin in Tablets

Elsevier B.V.
Publication Date
  • Analytical Chemistry > Spectroscopy
  • Analchem/0208001


A non-destructive, rapid and simple near infra red reflectance spectroscopic method was described for determination of anti-diabetic tablets. Partial least squares was applied to the Savitsky-Golay smoothed first derivative spectral data revealed over wavelength range 1000-2500 nm from 11 different pulverized tablet batches in 2-mm quartz cell. The results were agreed well with those obtained by the official British Pharmacopiea 1998 UV assay of metformin.

There are no comments yet on this publication. Be the first to share your thoughts.