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Olfactory mucosa, aluminosilicates and Alzheimer's disease

Authors
Journal
Neurobiology of Aging
0197-4580
Publisher
Elsevier
Publication Date
Volume
7
Issue
6
Identifiers
DOI: 10.1016/0197-4580(86)90126-0
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Age-related degenerative changes in mucosal epithelium may result in decreased barrier function. This change may predispose the adjacent brain areas to invasion by organisms and toxins leading to regional tissue damage as seen in Alzheimer's disease (AD). Age-related decrease in nasal mucosal barrier function, however, would explain some but not all the pathologic changes associated with AD.

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