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Heck reactions in solid phase synthesis

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
35
Issue
48
Identifiers
DOI: 10.1016/0040-4039(94)88389-0
Disciplines
  • Chemistry
  • Mathematics

Abstract

Abstract Heck reactions of polymer bound aryl iodide ( 1) or styrene ( 2) with olefins or aryl halides generally gave good yields of products of high purity. The methodology developed can be applied as a convenient procedure for generating 1,2-disubstituted olefins in combinatorial chemical libraries.

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