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An overlapping site model for the lipid annulae of membrane proteins

Authors
Journal
FEBS Letters
0014-5793
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Volume
151
Issue
2
Identifiers
DOI: 10.1016/0014-5793(83)80090-8
Keywords
  • Membrane Proteins
  • Lipid-Protein Interactions
  • Fatty Acids
  • Cardiolipin
Disciplines
  • Biology

Abstract

Abstract A model is presented for the binding of phospholipids and related molecules to membrane proteins, based on a fixed number of binding sites for fatty acyl chains. It is shown that in such a model, statistical factors favour binding of single chain molecules such as fatty acids when present at low concentrations in mixtures with phospholipids

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