Affordable Access

Publisher Website

Cultured human neural cells accumulate a heat-shock protein during acute herpes simplex virus infection

Authors
Journal
Neuroscience Letters
0304-3940
Publisher
Elsevier
Publication Date
Volume
61
Issue
3
Identifiers
DOI: 10.1016/0304-3940(85)90484-7
Keywords
  • Human Neural Cell
  • Herpes Simplex Virus
  • Heat-Shock Protein
Disciplines
  • Biology

Abstract

Abstract Herpes simplex virus-1 (HSV-1) infection of cultured human neural cells causes the accumulation of a host cell-encoded nuclear protein identified as a 57,000 mol.wt. stress protein by monoclonal antibody TI56. This protein is cell cycle-related in fibroblasts, may mediate host cell control during HSV infection and could play a role in the regulation of HSV latency.

There are no comments yet on this publication. Be the first to share your thoughts.