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Quantification of acute myocardial injury by ShMOLLI T1-Mapping, T2-weighted and late gadolinium imaging in patients presenting with chest pain, positive troponins and non-obstructive coronary arteries

Authors
Journal
Journal of Cardiovascular Magnetic Resonance
1097-6647
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
13
Identifiers
DOI: 10.1186/1532-429x-13-s1-p16
Keywords
  • Poster Presentation
Disciplines
  • Medicine

Abstract

Quantification of acute myocardial injury by ShMOLLI T1-Mapping, T2-weighted and late gadolinium imaging in patients presenting with chest pain, positive troponins and non-obstructive coronary arteries POSTER PRESENTATION Open Access Quantification of acute myocardial injury by ShMOLLI T1-Mapping, T2-weighted and late gadolinium imaging in patients presenting with chest pain, positive troponins and non- obstructive coronary arteries Vanessa M Ferreira1*, Stefan K Piechnik1, Erica Dall’Armellina1, Theodoros D Karamitsos1, Jane M Francis1, Matthias G Friedrich2, Matthew D Robson1, Stefan Neubauer1 From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011 Objective To assess the ability of ShMOLLI T1-mapping in detect- ing acute myocardial injury in patients with chest pain, positive troponins and non-obstructive coronary arteries. Background To diagnose acute myocardial injury of varying etiolo- gies, cardiovascular magnetic resonance (CMR) techni- ques must be sensitive to global and focal changes. ShMOLLI T1-mapping permits quantitative myocardial characterization without contrast agents or reference regions. We compare ShMOLLI T1-mapping against traditional CMR imaging modalities. Methods 16 patients (8 men, mean age 51±16 years) with acute chest pain, Troponin I >1.0 ug/L and non-obstructive coronary arteries underwent 1.5T CMR imaging within 7 days of presentation (median 3 days). CMR protocol included Shortened Modified Look-Locker inversion recovery (ShMOLLI) for T1-mapping, T2-STIR and late gadolinium enhancement (LGE) imaging. Regional wall motion was assessed with SSFP cines. Volumetric frac- tions of injured myocardium were quantified by (1) T2 signal intensity (SI) of myocardium:skeletal muscle >1.9:1; (2) T1>110% of normal myocardial T1; and (3) LGE SI>2SD of remote myocardium SI. Results 8 cases of myocarditis, 4 cases of Takotsubo cardiomyo- pathy and 4 cases of myocardial infarction were diag- nosed based on CMR findings. All demonstrat

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