Abstract The atmospheric ozone layer serves as a protective filter against (part of) the harmful ultraviolet (UV) radiation from the sun. The depletion of the ozone layer, which was observed on a global scale over the past decades, is most probably caused by the global emission of halocarbons, and leads to an increase in UV at groundlevel, and thus, to increases in UV-related risks, like skin cancer incidence. Using satellite data on ozone depletion, a location specific estimate of changes in UV-levels is made for Europe. A source-risk model is used to illustrate effects of countermeasures on future skin cancer risks. Geographical differences and uncertainties are indicated.