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Rheumatoid cachexia: a complication of rheumatoid arthritis moves into the 21st century

Authors
Journal
Arthritis Research & Therapy
1478-6354
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
11
Issue
2
Identifiers
DOI: 10.1186/ar2658
Source
Legacy
Keywords
  • Editorial
Disciplines
  • Medicine

Abstract

Rheumatoid cachexia, loss of muscle mass and strength and concomitant increase in fat mass, is very common in patients with rheumatoid arthritis (RA). Despite great advances in the treatment of RA, it appears that rheumatoid cachexia persists even after joint inflammation improves. Rheumatoid cachexia may be an important risk factor for cardiovascular disease and excess mortality in RA. In this issue of Arthritis Research & Therapy, Elkan and colleagues demonstrate a link between rheumatoid cachexia and metabolic syndrome, further reinforcing the need for therapy directed beyond inflammation and at the metabolic consequences of RA.

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