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Effect of hypothermia on coagulation functions in Sprague-Dawley rats with uncontrolled hemorrhagic shock

Authors
Journal
Critical Care
1364-8535
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
15
Identifiers
DOI: 10.1186/cc9859
Keywords
  • Poster Presentation
Disciplines
  • Medicine

Abstract

Prelims.indd P1 Eff ects of thyroid hormones on major cardiovascular risk in acute coronary syndromes A Bayrak1, A Bayır2, K Uçar Karabulut3 1Selçuk University, Meram Faculty of Medicine, Konya, Turkey; 2Selçuk University, Selçuklu Faculty of Medicine, Emergency Department, Konya, Turkey; 3Emergency Sercice of Şırnak State Hospital, Şırnak, Turkey Critical Care 2011, 15(Suppl 1):P1 (doi: 10.1186/cc9421) Introduction In this study we aimed to investigate the relationship between thyroid hormone abnormalities and major cardiovascular events and sudden cardiac death at 3 and 6 months after discharge in patients who were admitted to the Emergency Department with acute coronary syndrome. Methods The study group included 110 patients without known thyroid dysfunction who were referred to the Emergency Department with acute coronary syndrome. FT3, FT4 and TSH levels were measured in all patients on admission. Patients were divided into STEMI, NSTEMI and UAP groups. Patient records were checked at 3 and 6 months of discharge in terms of sudden cardiac death and major cardiovascular events. The relationship between thyroid hormone levels and acute cardiac death and major cardiovascular disorders at 3 and 6 months of discharge was evaluated. Results The mean TSH, FT3 and FT4 levels of the study group versus control group were as follows: TSH levels of study group 1.87 ± 1.73 μIU/ ml, FT3 3.2 ± 1.34 pg/ml, FT4 1.45 ± 0.64 ng/dl. Abnormalities in the thyroid function tests were noted in 26 patients (23.6%). Of these seven patients (6.36%) had subclinical hypothyroidism, two patients (1.8%) had euthyroid sick syndrome and 10 patients (9%) had high serum FT4 levels despite normal FT3 and TSH values. Conclusions We noted subclinical hypothyroidism, less frequently euthyroid sick syndrome and hyperthyroidism. No relationship was noted between thyroid hormone levels and sudden cardiac death and major cardiovascular disorders at 3 and 6 months follow-up. However, studies including l

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