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A Survey of Marine Natural Compounds and Their Derivatives with Anti-Cancer Activity Reported in 2010

Authors
Type
Published Article
Journal
Molecules
Publisher
MDPI AG
Publication Date
Jun 29, 2011
Volume
16
Issue
12
Pages
5646–5646
Identifiers
DOI: 10.3390/molecules16075629
Source
LBMCC
Keywords
License
Green

Abstract

Although considerable progress in oncology therapeutics has been achieved in the last century, cancer remains one of major death causes in the World and for this reason, the development of novel cancer drugs remains a pressing need. Natural marine compounds represent an interesting source of novel leads with potent chemotherapeutic or chemo-preventive activities. In the last decades, structure-activity-relationship studies have led to the development of naturally-derived or semi-synthetic analogues with improved bioactivity, a simplified synthetic target or less toxicity. We aim here to review a selection of natural compounds with reported anticancer activity isolated of marine sources and their associated analogues published in 2010.

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