Affordable Access

A new rRNA processing mutant of Saccharomyces cerevisiae.

Authors
  • L Lindahl
  • R H Archer
  • J M Zengel
Publication Date
Jan 25, 1992
Source
PMC
License
Unknown

Abstract

We have identified from a collection of temperature sensitive yeast mutants strains which fail to process rRNA normally. Characterization of one such mutant is reported here. This strain accumulates increased amounts of the 35S primary transcript, '24S' molecules extending from the transcription start site to the 5.8S region, and two classes of 5.8S rRNA with 5' extensions of 7 and 149 bases, respectively. We show that this pleiotropic change in the rRNA processing pattern is due to a single mutation. Possible models for the function of the mutated gene are discussed.

Report this publication

Statistics

Seen <100 times