Abstract This study sought to examine the complex interactive impact of major stress and minor stressors on the relation between dietary restraint and binge eating. Participants were 497 undergraduate females who completed an online questionnaire that included measures of binge eating (modified version of the bulimia scale of the Eating Disorder Inventory-2; EDI-2), major life stressors (the Social Readjustment Rating Scale; SRRS), minor stressors (Daily Stress Inventory; DSI), and dietary restraint (Restraint Scale; RS). A hierarchal linear regression revealed a significant three-way interaction among dietary restraint, life event stress, and daily stress that accounted for a significant proportion of the variance in binge eating above and beyond all main effects and two-way interactions. Findings suggested that the interactive relationship among dietary restraint and daily stress is present only under conditions of high life event stress. Overall, the relationship between dietary restraint and binge eating appears to be quite complex and dependent upon differential levels of daily and life event stressors.