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A new strategy for the synthesis of axially chiral biaryl compounds

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
35
Issue
48
Identifiers
DOI: 10.1016/0040-4039(94)88406-4

Abstract

Abstract Axially chiral compounds can be synthesized in high atropisomeric purity by aryl coupling of a conformationally locked dihydroxy-stilbenoids, which are readily available via Sharpless asymmetric dihydroxylation of olefin precursors.

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