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Antiviral activity of new triterpenic derivatives

Authors
Journal
Pharmacological Research
1043-6618
Publisher
Elsevier
Publication Date
Volume
29
Issue
4
Identifiers
DOI: 10.1016/1043-6618(94)80057-x
Keywords
  • Antivirals
  • Triterpenes

Abstract

Abstract Twenty-seven triterpenec derivatives of glycyrrhetihic, oleanolic, ursolic and maslinic acid were tested for antiviral and cytotoxic properties. Twelve of them showed apparent antiviral activity against at least one of the tested viruses. The most active compounds were PAS-T45 and 48 which exerted a protection index of 4 on vaccinia virus.

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