Affordable Access

Publisher Website

In vitro and ex vivo responses of bovine lymphocytes to hypodermin C, an enzyme secreted byHypoderma lineatum(Insect Oestridae)

Authors
Journal
Veterinary Immunology and Immunopathology
0165-2427
Publisher
Elsevier
Publication Date
Volume
36
Issue
2
Identifiers
DOI: 10.1016/0165-2427(93)90104-c
Disciplines
  • Biology

Abstract

Abstract The aim of this work was to determine if Hypodermin C (HC), an enzyme secreted by Hypoderma spp. larvae during their migration, is able to depress the lymphocyte response to mitogens and antigens. HC, when added to the lymphocyte culture, was able to influence the response of naive-calf lymphocytes to phytohemagglutinin. Secondly, injections of HC to uninfested and previously-infested cattle did not modify the proliferative response of the lymphocytes of these animals to mitogens. Thirdly, injections of HC to infested cattle did not negatively influence the specific humoral and cellular responses.

There are no comments yet on this publication. Be the first to share your thoughts.