Affordable Access

Publisher Website

Cleavage of a nucleosidic oxetane with carbanions: synthesis of a highly promising candidate for anti-HIV agents — a phosphonate isostere of AZT 5′-phosphate

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
30
Issue
19
Identifiers
DOI: 10.1016/s0040-4039(01)80452-4

Abstract

Abstract A phosphonate analogue of 3′-azido-3′-deoxythymidine (AZT) 5′-phosphate was synthesized via nucleophilic ring-opening of a nucleosidic oxetane with (RO) 2POCH 2Li as a key reaction step.

There are no comments yet on this publication. Be the first to share your thoughts.