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Persistence of gastrointestinal-specific antigens in primary culture of human colon epithelium

Authors
Journal
Experimental Cell Research
0014-4827
Publisher
Elsevier
Publication Date
Volume
49
Issue
3
Identifiers
DOI: 10.1016/0014-4827(68)90201-2

Abstract

Abstract The antigenic changes in primary cultures of human colon epithelium have been studied by immunofluorescence using a heterologous gastrointestinal-specific antiserum and a serum containing autoantibody to intestine from a patient with ulcerative colitis. The number of antigen-positive cells and the amount of antigen in individual cells both decreased, but antigen could still be detected in the cultures as long as they survived, i.e. about 20 days in these experiments.

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