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An efficient synthesis of tetrasubstituted cyclohexyl-1,2-diamines

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
46
Issue
11
Identifiers
DOI: 10.1016/j.tetlet.2005.01.072

Abstract

Abstract The synthesis of symmetrically tetrasubstituted diamines derived from the ( R, R)-cyclohexyl-1,2-diamine is reported. We comment on the efficiency of this sequential substitution approach as a method for the synthesis of tetrasubstituted diamines and discuss the acceptable substitution pattern for this methodology.

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