Affordable Access

Publisher Website

Breast cancer risk-assessment models

Authors
Journal
Breast Cancer Research
1465-5411
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
9
Issue
5
Identifiers
DOI: 10.1186/bcr1750
Keywords
  • Review
Disciplines
  • Biology

Abstract

There are two main questions when assessing a woman for interventions to reduce her risks of developing or dying from breast cancer, the answers of which will determine her access: What are her chances of carrying a mutation in a high-risk gene such as BRCA1 or BRCA2? What are her risks of developing breast cancer with or without such a mutation? These risks taken together with the risks and benefits of the intervention will then determine whether an intervention is appropriate. A number of models have been developed for assessing these risks with varying degrees of validation. With further improvements in our knowledge of how to integrate risk factors and to eventually integrate further genetic variants into these models, we are confident we will be able to discriminate with far greater accuracy which women are most likely to develop breast cancer.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

[Models for risk assessment and prediction in brea...

on Zhonghua liu xing bing xue za... October 2009

Comparing breast cancer risk assessment models.

on JNCI Journal of the National C... May 19, 2010

Breast cancer risk-assessment models.

on Breast Cancer Research 2007

Available models for breast cancer risk assessment...

on Journal of the American Colleg... December 2003
More articles like this..