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The preparation and clinical administration of lyophilized platelet material to children with acute leukemia and aplastic anemia

Authors
Journal
The Journal of Pediatrics
0022-3476
Publisher
Elsevier
Publication Date
Volume
49
Issue
5
Identifiers
DOI: 10.1016/s0022-3476(56)80138-8

Abstract

Summary Lyophilized platelet material has been administered intravenously to patients with secondary thrombocytopenia without toxic or thromboembolic sequelae. Defective prothrombin consumption has been corrected by this platelet preparation, but its effects on hemostasis, although suggestive, require further investigation. The safety and stability of this material indicate the possibility of making various platelet factors, such as the antifibrinolysin, antiheparin, and thromboplastin-generating activity, readily available.

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