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Chemotactic Responsiveness of Human Alveolar Macrophages: Effects of Cigarette Smoking

Authors
Publication Date
Source
PMC
Keywords
  • Pathogenic Mechanisms
  • Ecology
  • And Epidemiology
Disciplines
  • Medicine

Abstract

Pulmonary alveolar macrophages from six cigarette smokers demonstrated higher random migration and greater chemotactic responsiveness to casein than did macrophages from seven nonsmokers. These observations are consistent with the concept that pulmonary macrophages are metabolically activated by cigarette smoking.

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