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Investigation on the carcinogenicity of emission condensate from brown coal-fired residential furnaces applied to mouse skin

Authors
Journal
Cancer Letters
0304-3835
Publisher
Elsevier
Publication Date
Volume
25
Issue
1
Identifiers
DOI: 10.1016/s0304-3835(84)80032-4

Abstract

Summary Flue gas condensate emitted from brown coal-fired stoves was tested in 3 dosages applied chronically to the skin of female CFLP mice twice a week over a period of 104 weeks. To answer the question which portion of the total carcinogenicity results from benzo[ a]pyrene (BaP), this compound was taken as reference substance. The probit and Weibull analysis of the results showed a linear doseresponse relationship for both tumor incidences and tumor induction times. The amount of BaP in the emission condensate (0.593 mg/g condensate) contributes about 15% to the total carcinogenic effect of the brown coal flue gas condensate.

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