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Opportunities at the interface of chemistry and biology

Authors
Journal
Trends in Cell Biology
0962-8924
Publisher
Elsevier
Publication Date
Volume
9
Issue
12
Identifiers
DOI: 10.1016/s0962-8924(99)01682-7
Keywords
  • Chemical
  • Biological Synthesis
  • Molecular Function
Disciplines
  • Biology
  • Chemistry
  • Mathematics

Abstract

Abstract The combination of the tools and principles of chemistry, together with the tools of modern molecular biology, allow us to create complex synthetic and natural molecules, and processes with novel biological, chemical and physical properties. This article illustrates the tremendous opportunity that lies at this interface of chemistry and biology by describing a number of examples, ranging from efforts to expand the genetic code of living organisms to the use of combinatorial methods to generate biologically active synthetic molecules.

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