Affordable Access

Publisher Website

α-Melanocyte-stimulating Hormone in Normal Human Physiology and Disease States

Authors
Journal
Trends in Endocrinology and Metabolism
1043-2760
Publisher
Elsevier
Publication Date
Volume
11
Issue
8
Identifiers
DOI: 10.1016/s1043-2760(00)00296-4
Keywords
  • Neuroimmunomodulation
  • Inflammation
  • α-Msh
  • Proopiomelanocortin
  • Melanocortin Receptors

Abstract

Abstract Over the past two decades, research in animal models has indicated that α-melanocyte-stimulating hormone (α-MSH) has potent anti-inflammatory properties. Furthermore, recent data show that the peptide has antimicrobial effects and probably contributes to innate immunity. α-MSH, which is produced by many extrapituitary human cells, should no longer be considered solely a pituitary hormone; rather, it should be viewed as a ubiquitous modulatory peptide.

There are no comments yet on this publication. Be the first to share your thoughts.