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Power spectra and cooperativity of a calcium-regulated cation channel

Authors
Journal
Biophysical Journal
0006-3495
Publisher
Elsevier
Publication Date
Volume
66
Issue
1
Identifiers
DOI: 10.1016/s0006-3495(94)80747-7
Disciplines
  • Computer Science
  • Physics

Abstract

In this article we show that a channel complex of cooperatively interacting subunits can produce a power law spectrum with the slope of the spectrum depending on the strength of the cooperative interaction. The effects of cooperativity are explored via a computational model of a calcium-regulated cation channel for which new data is presented. The results, which concern "flickering" conductances, are correlated with prior work on critical fluctuations in the Ising model of ferromagnetism.

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