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Statistical analysis of the Shapley value for microarray games

Authors
Journal
Computers & Operations Research
0305-0548
Publisher
Elsevier
Publication Date
Volume
37
Issue
8
Identifiers
DOI: 10.1016/j.cor.2009.02.016
Keywords
  • Cooperative Game Theory
  • Shapley Value
  • Microarray Gene Expression
  • Non-Parametric Bootstrap Methods
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Game theory may be helpful to analyze the relevance of genes in determining a specific biological condition or response of interest (e.g. a disease of interest) in a population of cells. The first goal of this paper is to understand how accurate is the relevance index provided by the Shapley value on games arising from microarray experiments. Such a question is the prelude to the second subject of this paper, which concerns comparison between the relevance indices under different biological conditions.

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