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Mechanisms for recovery of motor function following cortical damage

Authors
Publisher
Elsevier Ltd
Publication Date
Volume
16
Issue
6
Identifiers
DOI: 10.1016/j.conb.2006.10.004
Disciplines
  • Biology
  • Medicine

Abstract

Recent studies of focal injury to the cerebral cortex have demonstrated that the remaining, intact tissue undergoes structural and functional changes that could play a substantial role in neurological recovery. New information regarding the molecular and cellular environment in the adjacent, intact tissue has suggested that waves of growth promotion and inhibition modulate the self-repair processes of the brain. Furthermore, recent studies have documented widespread neurophysiological and neuroanatomical changes in regions remote from a focal cortical injury, suggesting that entire cortical networks participate in the recovery process.

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