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Local infusion of infliximab for the treatment of acute joint inflammation

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.org Page ( 1 ) AAOS does not endorse any treatments, procedures, products, or physicians referenced herein. This information is provided as an educational service and is not intended to serve as medical advice. Anyone seeking specifi c orthopaedic advice or assistance should consult his or her orthopaedic surgeon, or locate one in your area through the AAOS “Find an Orthopaedist” program on Copyright ©1995-2013 by the American Academy of Orthopaedic Surgeons. Arthritis of the Hand The hand and wrist have multiple small joints that work together to produce motion, including the fi ne motion needed to thread a needle or tie a shoelace. When the joints are aff ected by arthritis, activities of daily living can be diffi cult. Arthritis can occur in many areas of the hand and wrist and can have more than one cause. Over time, if the arthritis is not treated, the bones that make up the joint can lose their normal shape. This causes more pain and further limits motion. Description Simply defi ned, arthritis is infl ammation of one or more of your joints. The most common types of arthritis are osteoarthritis and rheumatoid arthritis, but there are more than 100 diff erent forms. Healthy joints move easily because of a smooth, slippery tissue called articular cartilage. Cartilage covers the ends of bones and provides a smooth gliding surface for the joint. This smooth surface is lubricated by a fl uid that looks and feels like oil. It is produced by the joint lining called synovium. Disease When arthritis occurs due to disease, the onset of symptoms is gradual and the cartilage decreases slowly. The two most common forms of arthritis from disease are osteoarthritis and rheumatoid arthritis. Osteoarthritis is much more common and generally aff ects older people. Also known as “wear and tear” arthritis, osteoarthritis causes cartilage to wear away. It appears in a predictable pattern in certain joints. Rheumatoid arthritis is a chronic disease that

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