Affordable Access

Publisher Website

An electron microscopic study of the structure of the small intestine in Whipple's disease

Authors
Journal
Journal of Ultrastructure Research
0022-5320
Publisher
Elsevier
Publication Date
Volume
10
Identifiers
DOI: 10.1016/s0022-5320(64)90026-7
Disciplines
  • Medicine

Abstract

The periodic acid-Schiff staining inclusion in the macrophages of Whipple's disease has been demonstrated to be a complex body, possibly related to the rods found extracellularly in the submucosa. The fine structure of the rods demonstrates several alternating osmiophilic and less dense layers with a shaggy coat. These bodies average 200 m μ in cross section and are about 1500 m μ in length. Their possible role in the pathogenesis of Whipple's disease has been discussed, particularly in relation to what is known about the fine structure of phagocytized bacterial cells.

There are no comments yet on this publication. Be the first to share your thoughts.