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6-(ω-Guanidinoalkyl)- and 6-(ω-imidazolinaminoalkyl)-5,6,7,8-tetrahydrodibenz[c,e]azocines

Institute of Organic Chemistry and Biochemistry
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Guanidine derivatives of 5,6,7,8-tetrahydrodibenz[c,e]azocine IV and V were prepared by a three-step synthesis starting from 5,6,7,8-tetrahydrodibenz[c,e]azocine (I) via the corresponding 6-(ω-cyanoalkyl) II and 6-(ω-aminoalkyl) derivatives III; finaly, compounds III were treated with either methylisothiuronium halide or methylthioimidazolinium halide.

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