Abstract The limited glass forming ability (GFA) and deficient plasticity are two longstanding bottlenecks for the applications of bulk metallic glasses (BMGs) as structural materials. In this article, we report a TiZr-based BMG with nominal composition of Ti36.2Zr30.3Cu8.3Fe4Be21.2 (at.%) which possesses exceptional GFA and remarkable compressive plasticity simultaneously. The alloy ingot in weight of 150g can be solidified into an amorphous state, indicating an exceptional GFA – the critical size for glass forming of the current BMG is estimated over 50mm. The plasticity of about 8% was obtained from the as-cast 2-mm-diameter rod with an aspect ratio of 2, concomitant obvious work hardening effect. The present BMG possessing exceptional GFA and remarkable compressive plasticity simultaneously may have a scientific importance on developing BMGs for structural applications.