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The use of δ13C isotope ratio mass spectrometry for methamphetamine profiling: Comparison of ephedrine and pseudoephedrine-based samples to P2P-based samples

Authors
Journal
Forensic Science International
0379-0738
Publisher
Elsevier
Volume
234
Identifiers
DOI: 10.1016/j.forsciint.2013.10.022
Keywords
  • Forensic Science
  • Methamphetamine Profiling
  • Isotope Ratio Mass Spectrometry
  • Phenyl-2-Propanone
  • Pseudoephedrine
  • Ephedrine

Abstract

Abstract Differentiating methamphetamine samples produced from ephedrine and pseudoephedrine from phenyl-2-propanone precursors is critical for assigning synthetic route information for methamphetamine profiling. The use of isotope ratio mass spectrometry data is now a key component for tracking precursor information. Recent carbon (δ13C) isotope results from the analysis of numerous methamphetamine samples show clear differentiation for ephedrine and pseudoephedrine-produced samples compared to P2P-produced samples. The carbon isotope differences were confirmed from synthetic route precursor studies.

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