Affordable Access

Publisher Website

Fatal liver failure: molecular evidence for chronic active Epstein-Barr virus infection

Authors
Journal
Annals of Diagnostic Pathology
1092-9134
Publisher
Elsevier
Publication Date
Volume
12
Issue
5
Identifiers
DOI: 10.1016/j.anndiagpath.2007.01.008
Keywords
  • Epstein-Barr Virus
  • Infectious Mononucleosis
  • Liver Failure
Disciplines
  • Medicine

Abstract

Abstract Epstein-Barr virus (EBV) infection is a benign disease, which may occasionally be fatal, particularly in children and immunocompromised patients. Epstein-Barr virus infection is rare in elderly subjects and seems to have a self-limited course. A case of fatal liver failure due to chronic active EBV infection in a 75-year-old man is described. The etiology was established postmortem by cellular expression of EBV-DNA in liver and lymphatic tissue. This patient meets the diagnostic criteria of a case definition for a highly probable “severe chronic active EBV syndrome.” Either suspected or unsuspected, the long-term prognosis of this syndrome is poor and its mortality high.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Increased cell-free viral DNA in fatal cases of ch...

on Clinical Infectious Diseases April 1999

Fatal chronic active Epstein-Barr virus infection...

on European journal of gastroente... February 2004

Chronic, active Epstein-Barr virus infection.

on Current opinion in hematology January 2000
More articles like this..