Affordable Access

Development of Polymer Prosthetic Heart Valve - Fabrication and In Vitro Test-

Seoul National University College of Medicine
Publication Date
  • Prosthetic Heart Valve
  • Hydrodynamic Tester
  • Trileaflet Polymer Valve
  • Bileaflet Polymer Valve
  • Design
  • Medicine


Prosthetic heart valves (PHV) with various types and materials have been developed and used until now, but PHVs have various problems that need improving. A new type of polymer PHV have been developed to ameliorate these problems. A hydrodynamic tester has also been developed for the precise evaluation of hydrodynamic performance of the developed PHV. PHV are composed of polyurethane, a material commonly used in biomedical materials because of its good biocompatibility and mechanical properties. To investigate its hydrodynamic properties, a trileaflet and bileaflet type polymer valve was fabricated. The results of comparative tests with the 2 polymer valves and a mechanical valve showed that the trileaflet polymer valve had a better hydrodynamic performance than the others. Though the bileaflet polymer valve showed a higher pressure drop and regurgitation than the trileaflet valve due to thicker leaflet flection of the bileaflet valve, if its fabrication method and design were corrected, a better result could be expected. For a study of the long-term stability of the PHV, accelerated endurance tests and stress analysis of PHVs are needed.

There are no comments yet on this publication. Be the first to share your thoughts.


Seen <100 times