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Neat synthesis and antioxidant activity of α-aminophosphonates

Authors
Journal
Arabian Journal of Chemistry
1878-5352
Publisher
Elsevier
Identifiers
DOI: 10.1016/j.arabjc.2013.01.004
Keywords
  • Multi-Component Reaction
  • Amberlyst-15
  • Microwave Irradiation
  • Antioxidant Activity
Disciplines
  • Ecology
  • Geography

Abstract

Abstract A simple, efficient, and environmentally benign method for a three-component reaction of an amine, an aldehyde and diethyl phosphite catalyzed by Amberlyst-15 has been developed to afford α-amino phosphonates in high yields and short reaction times under solvent-free reaction conditions using microwave irradiation. The major advantages of the present method are inexpensive, ecofriendly and reusable catalyst and also studied their antioxidant activity of synthesized compounds.

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