Affordable Access

Strain driven fast osseointegration of implants

BioMed Central
Publication Date
  • Short Report
  • Biology
  • Design
  • Mathematics
  • Medicine

Abstract ral ss BioMed CentHead & Face Medicine Open AcceShort report Strain driven fast osseointegration of implants Ulrich Joos†, Andre Büchter†, Hans-Peter Wiesmann† and Ulrich Meyer* Address: Department of Cranio-Maxillofacial Surgery, University of Münster, Waldeyerstraße 30, D-48129 Münster, Germany Email: Ulrich Joos - [email protected]; Andre Büchter - [email protected]; Hans-Peter Wiesmann - [email protected]; Ulrich Meyer* - [email protected] * Corresponding author †Equal contributors Abstract Background: Although the bone's capability of dental implant osseointegration has clinically been utilised as early as in the Gallo-Roman population, the specific mechanisms for the emergence and maintenance of peri-implant bone under functional load have not been identified. Here we show that under immediate loading of specially designed dental implants with masticatory loads, osseointegration is rapidly achieved. Methods: We examined the bone reaction around non- and immediately loaded dental implants inserted in the mandible of mature minipigs during the presently assumed time for osseointegration. We used threaded conical titanium implants containing a titanium2+ oxide surface, allowing direct bone contact after insertion. The external geometry was designed according to finite element analysis: the calculation showed that physiological amplitudes of strain (500–3,000 ustrain) generated through mastication were homogenously distributed in peri-implant bone. The strain-energy density (SED) rate under assessment of a 1 Hz loading cycle was 150 Jm- 3 s-1, peak dislocations were lower then nm. Results: Bone was in direct contact to the implant surface (bone/implant contact rate 90%) from day one of implant insertion, as quantified by undecalcified histological sections. This effect was substantiated by ultrastructural analysis of intimate osteoblast attachment and mature collagen mineralisation at the titanium surface. We detected no loss in t

There are no comments yet on this publication. Be the first to share your thoughts.