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Depression in adolescents and young adults — polysomnographic and neuroendocrine aspects

Authors
Journal
Journal of Affective Disorders
0165-0327
Publisher
Elsevier
Publication Date
Volume
14
Issue
1
Identifiers
DOI: 10.1016/0165-0327(88)90069-9
Keywords
  • Sleep Eeg Variables
  • Dexamethasone Suppression Test
  • Major Depression
  • Adolescence

Abstract

Abstract The comparison of polysomnographic data between a group of nine major depressive adolescents, 12 minor depressive adolescents and 12 controls showed a significant difference in sleep efficiency index and in percentage of awakenings. Sleep efficiency was reduced in major depressive adolescents and the percentage of awakenings was increased. Pubertal stage did not appear to have any effect on sleep EEG recordings. The administration of dexamethasone provoked a suppression of cortisol secretion in 50% of major depressive adolescents. Pubertal stage did not appear to have any significant effect on cortisol level after DST.

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