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Tirofiban

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Identifiers
DOI: 10.1016/b978-008055232-3.62772-2
Keywords
  • Agent
Disciplines
  • Biology

Abstract

Tirofiban, an inhibitor of platelet aggregation, is a nonpeptide antagonist of the platelet glycoprotein IIb/IIIa receptor. Tirofiban, in combination with heparin, is indicated for the treatment of acute coronary syndrome. The effects of tirofiban are mediated through reversible antagonism of fibrinogen binding to the IIb/IIIa receptor …

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