Lymphosarcoma and reticulum cell sarcoma primarily involving skin with no obvious evidence of extracutaneous spread, are rare conditions. Thirty-two cases (12 lymphosarcoma and 20 reticulum cell sarcoma) were seen over a period of 30 years. The clinical features are described as well as the different modes of treatment in 31 of these patients. Sixteen of the 31 patients presented with lesions localised to one body region. Following treatment, seven are alive and free of disease, two of them having survived over seven years. Nine of the 16 patients died of unrelated disease, with their primary lesions well and with no evidence of spread, two of them having survived ten years. Fourteen of the 31 treated patients died of generalised disease, their mean survival following treatment being only 21·8 months.