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Cholera Toxin Notches Epithelial Junctions

Authors
Journal
Cell Host & Microbe
1931-3128
Publisher
Elsevier
Publication Date
Volume
14
Issue
3
Identifiers
DOI: 10.1016/j.chom.2013.08.009

Abstract

Cholera toxin (CT) is the factor responsible for watery diarrhea associated with Vibrio cholerae infection. In this issue, Guichard et al. (2013) report that CT compromises intestinal epithelium barrier function via cyclic AMP (cAMP)-induced disruption of Rab11- and exocyst-dependent delivery of endocytic recycling cargo to cell-cell junctions.

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