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The movement of single cells within solid tissue masses

Authors
Journal
Experimental Cell Research
0014-4827
Publisher
Elsevier
Publication Date
Volume
79
Issue
2
Identifiers
DOI: 10.1016/0014-4827(73)90473-4

Abstract

Abstract Individual heart and liver cells isolated from chick embryos labelled in ovo with 3H-thymidine were seeded, in culture, onto the surfaces of unlabelled, embryonic heart and liver tissue masses (both tissue fragments and cellular reaggregates). Single, labelled cells, as observed in autoradiographs, infiltrated the interiors of the tissue masses in most cases. These results might be unexpected in light of previous experiments and current notions of ‘contact inhibition of cell movement’.

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