Abstract 1. The clinical features of two groups of patients, each containing four in number and presenting certain types of vasomotor rhinitis, are described. 2. Cutaneous and subcutaneous tests indicate sensitiveness of the patients to molds. 3. Of the mold preparations used in testing, Alternaria and Trichopyton are the only two which have been determined to be the cause of symptoms. 4. Alternaria is commonly found in dust. 5. Trichophyton is a common parasite of the integument of man, and thus human contacts may provide allergenic material. 6. The gratifying results of specific desensitization with appropriate mold extracts are recorded. 7. The distinction between sensitiveness to molds and infection with molds is worthy of emphasis.