Abstract Different Nd:Y x Gd 1 − x VO 4 mixed crystals with low Nd ion concentrations were successfully grown by the Czochralski method. The influences of different Gd/Y ratio on the Nd:Y x Gd 1 − x VO 4 mixed crystal properties were also investigated for the first time. X-ray powder diffraction (XRPD) results showed that the constants of a, c and the dimensions of unit cell were linear with the Gd content in mixed crystal. The thermal and optical properties show some interesting changes. The laser experiments have proved that Nd:Y x Gd 1 − x VO 4 crystals are new good laser materials.