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The RAVEN toolbox and its use for generating a genome-scale metabolic model for Penicillium chrysogenum.

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Publisher
Public Library of Science
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Keywords
  • We Present The Raven (Reconstruction
  • Analysis And Visualization Of Metabolic Networks) Toolbox: A Software Suite That Allows For Semi-Aut
  • It Makes Use Of Published Models And/Or The Kegg Database
  • Coupled With Extensive Gap-Filling And Quality Control Features
  • The Software Suite Also Contains Methods For Visualizing Simulation Results And Omics Data
  • As Well As A Range Of Methods For Performing Simulations And Analyzing The Results
  • The Software Is A Useful Tool For System-Wide Data Analysis In A Metabolic Context And For Streamlin
  • The Raven Toolbox Workflow Was Applied In Order To Reconstruct A Genome-Scale Metabolic Model For Th
  • The Model Was Validated In A Bibliomic Study Of In Total 440 References
  • And It Comprises 1471 Unique Biochemical Reactions And 1006 Orfs
  • It Was Then Used To Study The Roles Of Atp And Nadph In The Biosynthesis Of Penicillin
  • And To Identify Potential Metabolic Engineering Targets For Maximization Of Penicillin Production

Abstract

The RAVEN toolbox and its use for generating a genome-scale metabolic model for Penicillium chrysogenum. - DTU Orbit (27/04/14) The RAVEN toolbox and its use for generating a genome-scale metabolic model for Penicillium chrysogenum.. / Agren, Rasmus; Liu, Liming; Shoaie, Saeed; Vongsangnak, Wanwipa; Nookaew, Intawat; Nielsen, Jens. In: P L o S Computational Biology, Vol. 9, No. 3, 2013, p. e1002980. Publication: Research - peer-review › Journal article – Annual report year: 2013

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