Affordable Access

Publisher Website

High-resolution CT imaging of the lung for patients with primary Sjögren’s syndrome

European Journal of Radiology
Publication Date
DOI: 10.1016/j.ejrad.2004.01.006
  • High-Resolution
  • Ct Imaging
  • Sjögren’S Syndrome
  • Biology
  • Medicine


Abstract Purpose: To assess pulmonary abnormalities in patients with primary Sjögren’s syndrome (PSS) using high-resolution computed tomography (HRCT). Material and methods: The HRCT scans of 24 patients with the diagnosis PSS were retrospectively reviewed regarding the presence, extension and distribution of 16 pathological findings. Results: Nineteen patients (79.2%) showed pathological findings and in five patients (21.8%) the HRCT scan was judged to be normal. A predominance of abnormalities in the lower lobes and subpleural areas was detected. The following pathologies were found: bronchiectasis, thin-walled cysts and small pulmonary nodules (46.2%), ground-glass attenuation and emphysema (37.8%), interlobular-septal thickening (29.4%), honeycombing (25.2%), bronchial wall thickening, tree-in-bud pattern (21.0%), mosaic perfusion (16.8%), architectural distortion (12.6%). Airspace consolidation, air trapping, large nodules (10–30 mm) and masses (>30 mm), mediastinal lymph node enlargement (>15 mm) and free pleural fluid were seen each in 4.2%. In 7 of the 11 patients with thin-walled cysts areas of ground-glass attenuation were detected. Conclusion: HRCT seems is contributive to the characterization of the wide variety of lung abnormalities in PSS. Airway disease alone or in association with the presence of varying degrees of interstitial disease represents the main findings in accordance with earlier reports. Unexpectedly, almost half of the patients had thin-walled cysts on the HRCT scans, which etiology is unclear but could be associated with areas of ground-glass attenuation indicating LIP.

There are no comments yet on this publication. Be the first to share your thoughts.


Seen <100 times

More articles like this

High-resolution CT imaging of the lung for patient...

on European Journal of Radiology November 2004

Lung manifestation in asymptomatic patients with p...

on Journal of thoracic imaging October 2001

Primary Sjögren's syndrome and associated lung dis...

on American Journal of Roentgenol... September 1997

Inspiratory and expiratory high-resolution CT find...

on American Journal of Roentgenol... January 1997
More articles like this..