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Histologic Subtype and Margin of Resection Predict Pattern of Recurrence and Survival for Retroperitoneal Liposarcoma

Authors
Publication Date
Source
PMC
Keywords
  • Original Papers And Discussions
Disciplines
  • Biology
  • Medicine

Abstract

Dedifferentiated subtype and incomplete resection are the most important factors associated with tumor specific death in patients with primary retroperitoneal liposarcoma. Microscopic positive margins, tumor burden and nephrectomy were not associated with disease specific survival. Despite an aggressive surgical approach, over 80% of patients with dedifferentiated histology will recur locally and 30% will metastasize to distant sites within 3 years of diagnosis.

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