Affordable Access

Publisher Website

Synthesis of iodobenzylidene and iodoethylidene acetals ofd-glucose

Authors
Journal
Carbohydrate Research
0008-6215
Publisher
Elsevier
Publication Date
Volume
301
Identifiers
DOI: 10.1016/s0008-6215(97)00088-8
Keywords
  • D-Glucose Acetals
  • Haloacetals
  • Iodine Labelling
  • Glut
  • Spect
Disciplines
  • Biology

Abstract

Abstract The synthesis of two iodinated acetals of d-glucose, analogues of d-glucose acetals which are known to interact with the glucose transport protein GluT, is presented. The iodobenzylidene acetal was obtained by acetalation of 1,2,3-tri- O-acetyl-d-glucopyranose, whereas the iodoethylidene acetal was prepared from the corresponding prop-2-enylidene derivative by an ozonation/reduction sequence, followed by iodination of the resulting hydroxyethylidene derivative. These two iodinated acetals have been prepared towards studies of the transport of d-glucose by SPECT.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Synthesis ofd-glucose-6-t

on Archives of Biochemistry and B... Jan 01, 1960

A stereoselective synthesis of pyruvic 4,6-acetals...

on Carbohydrate Research Jan 01, 1990

Synthesis ofd-erythroascorbic acid fromd-glucose

on Carbohydrate Research Jan 01, 1991
More articles like this..