Affordable Access

Publisher Website

Effect of hypophysectomy on α-melanotropin in discrete regions of the rat brain

Authors
Journal
Neuroscience Letters
0304-3940
Publisher
Elsevier
Publication Date
Volume
14
Identifiers
DOI: 10.1016/0304-3940(79)96160-3
Disciplines
  • Medicine

Abstract

Summary The effect of hypophysectomy on α-melanotropin (αMSH) concentrations in discrete brain regions was investigated. Hypophysectomy resulted in a 38–69% decrease in αMSH concentration in αMSH terminal regions 4 weeks after surgery. In contrast, the αMSH concentration in the arcuate nucleus, site of αMSH containing perikary, was unaffected by hypophysectomy. These results indicate that the brain αMSH system is distinct from, but related to that of the pituitary.

There are no comments yet on this publication. Be the first to share your thoughts.