Using a job matching model, this paper attempts to explain the gender difference in transitional probabilities between employment and unemployment status. The idea is that there exists an asymmetric gender difference in job matching and job separation costs because females are primarily responsible for household production. It is shown that females experience higher costs when being matched with a job than males do, but females face lower costs when being separated from a job than males do. Such a structure of job matching and separation costs generate an asymmetric gender difference in labor turnover. It means a lower probability of job matching for females, but a higher probability of job separation for males. This paper raises an important identification question between gender difference and gender discrimination.